Paget's disease of the breast (also known as Paget's disease of the nipple ) is a malignant condition that outwardly may have the appearance of eczema, with skin changes involving the nipple of the breast.
The condition occurs when Paget's cells, which are large and irregular, form in the skin of the nipple. Although Paget believed the cells were not cancerous, it was later proved that the cells were themselves malignant, in addition to indicating another underlying breast cancer. Since the condition in itself is often innocuous and limited to a surface appearance, it is sometimes dismissed, although actually indicative of a very serious underlying condition, breast cancer.
Extramammary Paget's disease (EMPD) has the same histologic features as Paget's disease of the breast but different locations.
Read more about Paget's Disease Of The Breast: Symptoms, Diagnosis, Treatment, Prognosis, Epidemiology, History
Famous quotes containing the words disease and/or breast:
“The artistic temperament is a disease that affects amateurs.... Artists of a large and wholesome vitality get rid of their art easily, as they breathe easily or perspire easily. But in artists of less force, the thing becomes a pressure, and produces a definite pain, which is called the artistic temperament.”
—Gilbert Keith Chesterton (1874–1936)
“The forehead and the little ears
Have gone where Saturn keeps the years;
The breast where roses could not live
Has done with rising and with falling.”
—Edwin Arlington Robinson (1869–1935)