The oxidation of primary alcohols to carboxylic acids is an important oxidation reaction in organic chemistry.
When a primary alcohol is converted to a carboxylic acid, the terminal carbon atom increases its oxidation state by four. Oxidants able to perform this operation in complex organic molecules, featuring other oxidation-sensitive functional groups, must possess substantial selectivity. The most common oxidants are potassium permanganate (KMnO4), Jones reagent, PDC in DMF, Heyns oxidation, ruthenium tetroxide (RuO4) and TEMPO.
Read more about Oxidation Of Primary Alcohols To Carboxylic Acids: Potassium Permanganate, Jones Oxidation, PDC in DMF (Corey and Schmidt), Heyns Oxidation, Two-step Oxidation of Alcohols To Acids Via Isolated Aldehydes
Famous quotes containing the words primary and/or acids:
“Wilful sterility is, from the standpoint of the nation, from the standpoint of the human race, the one sin for which the penalty is national death, race death; a sin for which there is no atonement.... No man, no woman, can shirk the primary duties of life, whether for love of ease and pleasure, or for any other cause, and retain his or her self-respect.”
—Theodore Roosevelt (1858–1919)
“The new American finds his challenge and his love in the traffic-choked streets, skies nested in smog, choking with the acids of industry, the screech of rubber and houses leashed in against one another while the townlets wither a time and die.”
—John Steinbeck (1902–1968)