Types
The two types of replication origin are:
- Narrow or broad host range
- High- or low-copy number
There are also significant differences between prokaryotic and eukaryotic origins of replication:
- Bacteria have a single circular molecule of DNA, and typically only a single origin of replication per circular chromosome.
- Archaea have a single circular molecule of DNA, and several origins of replication along this circular chromosome.
- Eukaryotes often have multiple origins of replication on each linear chromosome that initiate at different times (replication timing), with up to 100,000 present in a single human cell. Having many origins of replication helps to speed the duplication of their (usually) much larger store of genetic material. The segment of DNA that is copied starting from each unique replication origin is called a replicon.
Origins of replication are typically assigned names containing ori.
Read more about this topic: Origin Of Replication
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“Hes one of those know-it-all types that, if you flatter the wig off him, he chatter like a goony bird at mating time.”
—Michael Blankfort. Lewis Milestone. Johnson (Reginald Gardner)
“Science is intimately integrated with the whole social structure and cultural tradition. They mutually support one otheronly in certain types of society can science flourish, and conversely without a continuous and healthy development and application of science such a society cannot function properly.”
—Talcott Parsons (19021979)
“As for types like my own, obscurely motivated by the conviction that our existence was worthless if we didnt make a turning point of it, we were assigned to the humanities, to poetry, philosophy, paintingthe nursery games of humankind, which had to be left behind when the age of science began. The humanities would be called upon to choose a wallpaper for the crypt, as the end drew near.”
—Saul Bellow (b. 1915)