Types
The two types of replication origin are:
- Narrow or broad host range
- High- or low-copy number
There are also significant differences between prokaryotic and eukaryotic origins of replication:
- Bacteria have a single circular molecule of DNA, and typically only a single origin of replication per circular chromosome.
- Archaea have a single circular molecule of DNA, and several origins of replication along this circular chromosome.
- Eukaryotes often have multiple origins of replication on each linear chromosome that initiate at different times (replication timing), with up to 100,000 present in a single human cell. Having many origins of replication helps to speed the duplication of their (usually) much larger store of genetic material. The segment of DNA that is copied starting from each unique replication origin is called a replicon.
Origins of replication are typically assigned names containing ori.
Read more about this topic: Origin Of Replication
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