History
The evolution of oligonucleotide synthesis saw four major methods of the formation of internucleosidic linkages and has been reviewed in the literature in great detail.
Read more about this topic: Oligonucleotide Synthesis
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“... that there is no other way,
That the history of creation proceeds according to
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Do get done in this way, but never the things
We set out to accomplish and wanted so desperately
To see come into being.”
—John Ashbery (b. 1927)
“History is not what you thought. It is what you can remember. All other history defeats itself.
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This book or that, come to this hallowed place
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Ireland’s history in their lineaments trace;
Think where man’s glory most begins and ends
And say my glory was I had such friends.”
—William Butler Yeats (1865–1939)