History
The evolution of oligonucleotide synthesis saw four major methods of the formation of internucleosidic linkages and has been reviewed in the literature in great detail.
Read more about this topic: Oligonucleotide Synthesis
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“The whole history of civilisation is strewn with creeds and institutions which were invaluable at first, and deadly afterwards.”
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—Sébastien-Roch Nicolas De Chamfort (1741–1794)
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