ODU may stand for:

  • Odigo User File, a file extension used in Odigo Messenger
  • Ohio Dominican University in Columbus, Ohio, United States
  • Old Dominion University in Norfolk, Virginia, United States
  • Operational Dress Uniform, a work uniform of the United States Coast Guard
  • Optical channel Data Unit, the digital path layer for the Optical Transport Network (OTN)
  • Out-Door Unit, a unit used in microwave transmission