Early Research
Siddiqi’s early work was in plant embryology at Aligarh, and wheat genetics at the Indian Agricultural Institute in Delhi. At Glasgow University he did research for his PhD with Guido Pontecorvo on microbial genetics. He mapped the fine genetic structure of the pabA gene and discovered polarized negative interference in crossing-over. Later he showed that recombinant bacteria inherit labeled DNA of biparental origin. Siddiqi and his colleagues demonstrated that recombinant molecules can arise from conserved unreplicated DNA. In 1961, Siddiqi and Garen discovered suppressor of nonsense mutations in the gene for alkaline phosphatase. This work led to the elucidation of the stop codons in the genetic code and the mechanism of chain termination during protein synthesis.
Read more about this topic: Obaid Siddiqi
Famous quotes containing the words early and/or research:
“[In early adolescence] she becomes acutely aware of herself as a being perceived by others, judged by others, though she herself is the harshest judge, quick to list her physical flaws, quick to undervalue and under-rate herself not only in terms of physical appearance but across a wide range of talents, capacities and even social status, whereas boys of the same age will cite their abilities, their talents and their social status pretty accurately.”
—Terri Apter (20th century)
“The working woman may be quick to see any problems with children as her fault because she isn’t as available to them. However, the fact that she is employed is rarely central to the conflict. And overall, studies show, being employed doesn’t have negative effects on children; carefully done research consistently makes this clear.”
—Grace Baruch (20th century)