NXC may refer to:
- nxc, NX technology library
- Nanjing Xiaozhuang College, Jiangsu, People’s Republic of China
- Namco × Capcom, a turn-based strategy console game
- Not eXactly C, a high level language, similar to C, built on top of the Next Byte Codes compiler
- NYSE: NXC, Nuveen California Select Tax-Free Income Portfolio
- Abbreviations for subsidiaries of the National Express Group from the UK
- NXC Trains Limited
- National Express Coaches
- NXC-4720, an antibacterial developed by Nymox to treat E. coli contamination of meat