Nurses' Health Study - Design

Design

A cohort of nurses aged 30 to 55 were initially surveyed in 1976 and biennially thereafter. A second cohort of nurses were enrolled in 1989.

Over time additional questions have been added, most notably the dietary assessment added in 1980. Deaths, usually reported by kin or by postal authorities, were followed up. Where possible and permitted, in cases suggestive of cardiovascular disease/coronary heart disease the followup went beyond death certificates to gather available documentation from autopsy reports and other records. Mortality followup is better than 98 percent.

In 1996, over 16,000 children of women in the second Nurses' Health Study cohort were enrolled in their own follow-up study called the Growing Up Today Study, or GUTS.

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