Relevance
The NNT is an important measure in pharmacoeconomics. If a clinical endpoint is devastating enough (e.g. death, heart attack), drugs with a high NNT may still be indicated in particular situations. If the endpoint is minor, health insurers may decline to reimburse drugs with a high NNT. Even though NNT is an important measure in a clinical trial, it is infrequently included in medical journal articles reporting the results of clinical trials. There are several important problems with the NNT, involving bias and lack of reliable confidence intervals, as well as difficulties in excluding the possibility of no difference between two treatments or groups.
Read more about this topic: Number Needed To Treat
Famous quotes containing the word relevance:
“Wherever the relevance of speech is at stake, matters become political by definition, for speech is what makes man a political being.”
—Hannah Arendt (1906–1975)
“The most striking fault in work by young or beginning novelists, submitted for criticism, is irrelevance—due either to infatuation or indecision. To direct such an author’s attention to the imperative of relevance is certainly the most useful—and possibly the only—help that can be given.”
—Elizabeth Bowen (1899–1973)
“... whatever men do or know or experience can make sense only to the extent that it can be spoken about. There may be truths beyond speech, and they may be of great relevance to man in the singular, that is, to man in so far as he is not a political being, whatever else he may be. Men in the plural, that is, men in so far as they live and move and act in this world, can experience meaningfulness only because they can talk with and make sense to each other and to themselves.”
—Hannah Arendt (1906–1975)