Number Needed To Treat
The number needed to treat (NNT) is an epidemiological measure used in assessing the effectiveness of a health-care intervention, typically a treatment with medication. The NNT is the average number of patients who need to be treated to prevent one additional bad outcome (i.e. the number of patients that need to be treated for one to benefit compared with a control in a clinical trial). It is defined as the inverse of the absolute risk reduction. It was described in 1988. The ideal NNT is 1, where everyone improves with treatment and no one improves with control. The higher the NNT, the less effective is the treatment.
Variants are sometimes used for more specialized purposes. One example is number needed to vaccinate.
NNT values are time-specific. For example, if a study ran for 5 years and it was found that the NNT was 100 during this 5 year period, in one year the NNT would have to be multiplied by 5 to correctly assume the right NNT for only the one year period (in the example the one year NNT would be 500).
Read more about Number Needed To Treat: Derivation, Relevance, Example: Statins For Primary Prevention, Worked Example, Simple Examples
Famous quotes containing the words number, needed and/or treat:
“Even in ordinary speech we call a person unreasonable whose outlook is narrow, who is conscious of one thing only at a time, and who is consequently the prey of his own caprice, whilst we describe a person as reasonable whose outlook is comprehensive, who is capable of looking at more than one side of a question and of grasping a number of details as parts of a whole.”
—G. Dawes Hicks (1862–1941)
“The country needs the political work of women to-day as much as it has ever needed woman in any other work at any other time.”
—J. Ellen Foster (1840–1910)
“English people apparently queue up as a sort of hobby. A family man might pass a mild autumn evening by taking the wife and kids to stand in the cinema queue for a while and then leading them over for a few minutes in the sweetshop queue and then, as a special treat for the kids, saying “Perhaps we’ve time to have a look at the Number Thirty-One bus queue before we turn in.””
—Calvin Trillin (b. 1940)