Resistance
Resistance can develop quickly with as little as one mutation. Mutations occur in the enzymes that phosphorylate the drug to activate it.
Read more about this topic: Nucleoside Analogue
Famous quotes containing the word resistance:
“The aim of every political association is the preservation of the natural and imprescriptible rights of man. These rights are liberty, property, security and resistance to oppression.”
—French National Assembly. Declaration of the Rights of Man (drafted and discussed August 1789, published September 1791)
“Growing older, I have lost the need to be political, which means, in this country, the need to be left. I am driven into grudging toleration of the Conservative Party because it is the party of non-politics, of resistance to politics.”
—Kingsley Amis (1922–1995)
“It was not seen that woman’s place was in the home until she began to go out of it; the statement was a reply to an unspoken challenge, it was attempted resistance to irresistible change.”
—Rose Wilder Lane (1886–1965)