Resistance
Resistance can develop quickly with as little as one mutation. Mutations occur in the enzymes that phosphorylate the drug to activate it.
Read more about this topic: Nucleoside Analogue
Famous quotes containing the word resistance:
“He made no resistance whatever, and was stabbed in the back.... I must not dwell upon the fearful repast.... Words have no power to impress the mind with the exquisite horror of their reality.”
—Edgar Allan Poe (1809–1849)