Novum Instrumentum Omne

Novum Instrumentum omne was the first published New Testament in Greek (1516). It was prepared by Desiderius Erasmus (1469–1536) and printed by Johann Froben (1460–1527) of Basel. Although the first printed Greek New Testament was the Complutensian Polyglot (1514), it was the second to be published (1522). Erasmus used several Greek manuscripts housed in Basel, but some passages he translated from the Latin Vulgate.

Five editions of Novum Instrumentum omne were published. Of these four and five were not regarded as being so important as the third edition (1522), which was used by Tyndale for the first English New Testament (1526) and later by translators of the Geneva Bible and the King James Version. With the third edition, the Comma Johanneum was included. The Erasmian edition was the basis for the majority of modern translations of New Testament in the 16–19th centuries.