List of NaSSAs
The NaSSAs include the following agents:
- Aptazapine (CGS-7525A)
- Esmirtazapine (ORG-50,081)
- Mianserin (Bolvidon, Norval, Tolvon)
- Mirtazapine (Remeron, Avanza, Zispin)
- Setiptiline (Tecipul)
Notably, all of these compounds are analogues and are also classified as tetracyclic antidepressants (TeCAs) based on their chemical structures.
Recently, S32212, a structurally novel NaSSA with an improved selectivity profile (e.g., no antihistamine effects, etc.), has been developed. It has completed preliminary preclinical research and may go on to undergo clinical trials.
Read more about this topic: Noradrenergic And Specific Serotonergic Antidepressant
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