Nichol is a surname, and may refer to
- B. P. Nichol, Canadian poet
- Caleb Nichol, fictional character from The O.C.
- Gene Nichol, former College of William & Mary president
- Hailey Nichol, fictional character from The O.C.
- Helen Nichol, Canadian badminton player
- John Nichol (biographer), Scottish writer, son of John Pringle Nichol
- John Nichol (RAF officer), RAF Navigator shot down and captured in the first Gulf War
- John Lang Nichol, Canadian politician
- John Pringle Nichol, Scottish astronomer
- Joseph McGinty Nichol, American film director McG
- Phil Nichol, Canadian comedian
- Robert Nichol (Canadian politician), historical figure in Upper Canada
- Scott Nichol, Canadian ice hockey player
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