Native chemical ligation or NCL is an important extension of the chemical ligation field, a concept for constructing a large polypeptide formed by the assembling of two or more unprotected peptides segments. Especially, NCL is the most powerful ligation method for synthesizing native backbone proteins or modified proteins of moderate size (i.e., small proteins< 200 AA).
Read more about Native Chemical Ligation: Definition, Historical Context, Properties
Famous quotes containing the words native and/or chemical:
“The will to power can express itself only against resistances; it seeks that which resists it—this is the native tendency of the amoeba when it extends its pseudopodia and gropes around.”
—Friedrich Nietzsche (1844–1900)
“We are close to dead. There are faces and bodies like gorged maggots on the dance floor, on the highway, in the city, in the stadium; they are a host of chemical machines who swallow the product of chemical factories, aspirin, preservatives, stimulant, relaxant, and breathe out their chemical wastes into a polluted air. The sense of a long last night over civilization is back again.”
—Norman Mailer (b. 1923)