Cast
- Loren Dean as Dr. Mumford
- Hope Davis as Sofie Crisp
- Jason Lee as Skip Skipperton
- Alfre Woodard as Lily
- Mary McDonnell as Althea Brockett
- Pruitt Taylor Vince as Henry Follett
- Zooey Deschanel as Nessa Watkins
- Martin Short as Lionel Dillard
- David Paymer as Dr. Ernest Delbanco
- Jane Adams as Dr. Phyllis Sheeler
- Kevin Tighe and Dana Ivey as Mr. and Mrs. Crisp
- Ted Danson as Jeremy Brockett
- Jason Ritter as Martin Brockett
- Elisabeth Moss as Katie Brockett
- Robert Stack as Himself
- Simon Helberg as College Roommate
The film also features future Dancing with the Stars alum and winner Kelly Monaco in a small (non-speaking) role.
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