Multielectrode Array - Data Processing Methods

Data Processing Methods

The fundamental unit of communication of neurons is, electrically, at least, the action potential. This all-or-nothing phenomenon originates at the axon hillock, resulting in a depolarization of the intracellular environment which propagates down the axon. This ion flux through the cellular membrane generates a sharp change in voltage in the extracellular environment, which is what the MEA electrodes ultimately detect. Thus, voltage spike counting and sorting is often used in research to characterize network activity.

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