MRD may stand for:
- Multi Residential Design
- Mentoring, Research & Development
- Machine-readable dictionary
- Mad Rollin' Dolls Woman's Flat Track Roller Derby League in Madison, WI.
- Mandibular Repositioning Device, used to prevent snoring and improve breathing at night.
- Metal Raiders, a Yu-Gi-Oh! Trading Card Game booster pack.
- Movement for Restoration of Democracy is a political alliance in Pakistan.
- Marketing Requirements Document used in technology product development and planning.
- Motor Racing Developments Ltd. a racing car constructor better known as Brabham
- Medical records department
- Minimal Residual Disease low levels of leukaemia cells present in the body after or during treatment.
- Miss Dominican Republic (Spanish: Miss República Dominicana)
- Material-Ready Date is a way to refer to the date when all materials for a given project are to be available on-site.
- Mutant Response Division, a fictional Marvel Comics organization
- Multicast router discovery, a network protocol
- Manual Ringdown, a type of phone interface that requires manual signaling.
- Mandy Rice-Davies