Mmp3

MMP3

Identifiers Symbols MMP3; CHDS6; MMP-3; SL-1; STMY; STMY1; STR1 External IDs OMIM: 185250 MGI: 97010 HomoloGene: 20545 ChEMBL: 283 GeneCards: MMP3 Gene EC number 3.4.24.17

Gene Ontology
Molecular function	• metalloendopeptidase activity • calcium ion binding • zinc ion binding • protein complex binding
Cellular component	• extracellular region • proteinaceous extracellular matrix • extracellular space • nucleus • dendrite • intracellular membrane-bounded organelle • protein complex • cell body
Biological process	• response to hypoxia • proteolysis • female pregnancy • extracellular matrix disassembly • extracellular matrix organization • regulation of cell migration • collagen catabolic process • response to estradiol stimulus • response to lipopolysaccharide • response to tumor necrosis factor • wound healing • response to interleukin-1 • cellular response to amino acid stimulus • cellular response to cell-matrix adhesion
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 4314 17392 Ensembl ENSG00000149968 ENSMUSG00000043613 UniProt P08254 P28862 RefSeq (mRNA) NM_002422 NM_010809 RefSeq (protein) NP_002413 NP_034939 Location (UCSC) Chr 11:
102.71 – 102.71 Mb Chr 9:
7.45 – 7.46 Mb PubMed search

Stromelysin-1 also known as matrix metalloproteinase-3 (MMP-3) is an enzyme that in humans is encoded by the MMP3 gene. The MMP3 gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. MMP-3 has an estimated molecular weight of 54 kDa.