MMP3

MMP3

Identifiers Symbols MMP3; CHDS6; MMP-3; SL-1; STMY; STMY1; STR1 External IDs OMIM: 185250 MGI: 97010 HomoloGene: 20545 ChEMBL: 283 GeneCards: MMP3 Gene EC number 3.4.24.17

Gene Ontology
Molecular function metalloendopeptidase activity
calcium ion binding
zinc ion binding
protein complex binding
Cellular component extracellular region
proteinaceous extracellular matrix
extracellular space
nucleus
dendrite
intracellular membrane-bounded organelle
protein complex
cell body
Biological process response to hypoxia
proteolysis
female pregnancy
extracellular matrix disassembly
extracellular matrix organization
regulation of cell migration
collagen catabolic process
response to estradiol stimulus
response to lipopolysaccharide
response to tumor necrosis factor
wound healing
response to interleukin-1
cellular response to amino acid stimulus
cellular response to cell-matrix adhesion
Sources: Amigo / QuickGO
RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 4314 17392 Ensembl ENSG00000149968 ENSMUSG00000043613 UniProt P08254 P28862 RefSeq (mRNA) NM_002422 NM_010809 RefSeq (protein) NP_002413 NP_034939 Location (UCSC) Chr 11:
102.71 – 102.71 Mb Chr 9:
7.45 – 7.46 Mb PubMed search

Stromelysin-1 also known as matrix metalloproteinase-3 (MMP-3) is an enzyme that in humans is encoded by the MMP3 gene. The MMP3 gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. MMP-3 has an estimated molecular weight of 54 kDa.

Read more about MMP3:  Function, Gene Regulation, Structure