Mmp2

MMP2

Identifiers Symbols MMP2; CLG4; CLG4A; MMP-II; MONA; TBE-1 External IDs OMIM: 120360 MGI: 97009 HomoloGene: 3329 ChEMBL: 333 GeneCards: MMP2 Gene EC number 3.4.24.24

Gene Ontology
Molecular function	• metalloendopeptidase activity • serine-type endopeptidase activity • protein binding • zinc ion binding • metal ion binding
Cellular component	• extracellular region • proteinaceous extracellular matrix • extracellular space • nucleus • mitochondrion • plasma membrane • sarcomere
Biological process	• angiogenesis • response to hypoxia • blood vessel maturation • intramembranous ossification • proteolysis • embryo implantation • extracellular matrix disassembly • extracellular matrix organization • collagen catabolic process • face morphogenesis • bone trabecula formation • cellular response to amino acid stimulus
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 4313 17390 Ensembl ENSG00000087245 ENSMUSG00000031740 UniProt P08253 P33434 RefSeq (mRNA) NM_001127891 NM_008610 RefSeq (protein) NP_001121363 NP_032636 Location (UCSC) Chr 16:
55.42 – 55.54 Mb Chr 8:
92.83 – 92.85 Mb PubMed search

72 kDa type IV collagenase also known as matrix metalloproteinase-2 (MMP-2) and gelatinase A is an enzyme that in humans is encoded by the MMP2 gene.