MLP may stand for:
- Mary-Louise Parker, an American actress
- Mid-level practitioner, an identifier used by the U.S. DEA to monitor the distribution of controlled substances
- Mullan Pass VOR, an aviation navigational aid located at Mullan Pass, Montana.
- My Little Pony, a toy originating in the 1980s which has also spawned multiple TV shows, most notably:
- My Little Pony: Friendship Is Magic.