Messinger is a surname of Germanic origin. The name refers to:
- Alida Rockefeller Messinger (b. 1948), American philanthropist; daughter of John D. Rockefeller III
- Dominic Messinger (contemporary), American composer of soap-opera music
- Gertrude Messinger (1911–1995), American actress 1930s–1950s
- Jonathan Messinger (contemporary), American author and editor
- Ruth Messinger (b. 1940), American politician from New York City; unsuccessful candidate for Mayor of New York 1997
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