Developmental Origin
The origin of Merkel cells has been debated for over 20 years. Evidence from skin graft experiments in birds implies that they are neural crest derived, but experiments in mammals now demonstrate an epidermal origin.
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“Our theism is the purification of the human mind. Man can paint, or make, or think nothing but man. He believes that the great material elements had their origin from his thought.”
—Ralph Waldo Emerson (1803–1882)