Melzer may refer to the following:
- Hagen Melzer (b. 1959), German long-distance runner
- Hanna Melzer (1904-1960), German anti-Nazi activist, see m:de:Hanna Melzer
- Jean Melzer (b. 1926), Australian senator
- Jürgen Melzer (b. 1981), Austrian tennis player
- Manfred Melzer (b. 1944), German bishop, see m:de:Manfred Melzer
- Richard Melzer (b. 1979), American basketball player
- Werner Melzer (b. 1954), German footballer
- Abi Melzer (Melzer Verlag), German publishing house
- Lawrence Melzer (b. 1974), Jewish Scholar