Filmography
| Year | Title | Role | Notes |
|---|---|---|---|
| 1969 | Smith! | Extra | Uncredited |
| 1973 | The Harrad Experiment | ||
| 1975 | Night Moves | Delly Grastner | |
| The Drowning Pool | Schuyler Devereaux | ||
| Smile | Karen Love | ||
| 1976 | Once an Eagle | Jinny Massengale | TV mini-series |
| 1977 | The Garden | Young Girl | |
| One on One | The Hitchhiker | ||
| Joyride | Susie | ||
| 1978 | Daddy, I Don't Like it Like This | Girl in Hotel | TV movie |
| Steel Cowboy | Johnnie | TV movie | |
| 1981 | Roar | Melanie | |
| Underground Aces | Lucy | ||
| The Star Maker | Dawn Barnett Youngblood | TV movie | |
| She's in the Army Now | Pvt. Sylvie Knoll | TV movie | |
| Golden Gate | Karen | TV movie | |
| 1984 | Body Double | Holly Body | National Society of Film Critics Award for Best Supporting Actress Nominated — Golden Globe Award for Best Supporting Actress – Motion Picture Nominated — New York Film Critics Circle Award for Best Supporting Actress |
| 1985 | Fear City | Loretta | |
| Alfred Hitchcock Presents | Girl | TV series (1 episode) | |
| 1986 | Something Wild | Audrey Hankel aka Lulu | Nominated — Golden Globe Award for Best Actress – Motion Picture Musical or Comedy |
| 1988 | Cherry 2000 | Edith 'E' Johnson | Straight to video |
| The Milagro Beanfield War | Flossie Devine | ||
| Stormy Monday | Kate | ||
| Working Girl | Tess McGill | Boston Society of Film Critics Award for Best Actress Golden Globe Award for Best Actress – Motion Picture Musical or Comedy Nominated — Academy Award for Best Actress Nominated — BAFTA Award for Best Actress in a Leading Role Nominated — National Society of Film Critics Award for Best Actress |
|
| 1990 | Women and Men: Stories of Seduction | Lureen | TV movie |
| In the Spirit | Hadley | ||
| Pacific Heights | Patty Palmer | ||
| The Bonfire of the Vanities | Maria Ruskin | ||
| 1991 | Paradise | Lily Reed | |
| 1992 | Shining Through | Linda Voss | |
| A Stranger Among Us | Emily Eden | ||
| 1993 | Born Yesterday | Billie Dawn | |
| 1994 | Milk Money | V | |
| Nobody's Fool | Toby Roebuck | ||
| 1995 | Buffalo Girls | Dora DuFran | Nominated — Golden Globe Award for Best Supporting Actress – Series, Miniseries or Television Film |
| Now and Then | Tina 'Teeny' Tercell | ||
| Two Much | Betty Kerner | ||
| 1996 | Mulholland Falls | Katherine Hoover | |
| 1997 | Lolita | Charlotte Haze | |
| 1998 | Another Day in Paradise | Sid | Sant Jordi Award for Best Foreign Actress |
| Shadow of Doubt | Kitt Devereux | ||
| Celebrity | Nicole Oliver | ||
| 1999 | Crazy in Alabama | Lucille Vinson | Sant Jordi Award for Best Foreign Actress |
| RKO 281 | Marion Davies | Nominated — Emmy Award for Outstanding Supporting Actress – Miniseries or a Movie Nominated — Golden Globe Award for Best Supporting Actress – Series, Miniseries or Television Film |
|
| 2000 | Cecil B. Demented | Honey Whitlock | |
| Forever Lulu | Lulu McAfee | Released on DVD as Along for the Ride (2000) | |
| 2001 | Tart | Diane Milford | |
| 2002 | Searching for Debra Winger | Herself | |
| Stuart Little 2 | Margalo the Bird | Voice | |
| 2003 | The Night We Called It a Day | Barbara Marx | Nominated — Australian Film Institute Award for Best Actress in a Supporting Role |
| Shade | Eve | ||
| Tempo | Sarah | ||
| 2005 | Heartless | Miranda Wells | TV movie |
| 2007 | Viva Laughlin | Bunny Baxter | TV series (2 episodes) |
| 2010 | Nip/Tuck | Brandie Henry | TV series (1 episode) |
| 2011 | Hot in Cleveland | Herself | Episode: "Sisterhood of the Traveling SPANX" |
| 2012 | American Housewife | Leila | Lifetime original series (Unaired) |
| Dino Time | Tyra | voice |
Read more about this topic: Melanie Griffith