Magnum (from Latin: magnum, neuter (nominative singular) of magnus neutral form, meaning great) may refer to several things:
- Moses Magnum, a Marvel Comics villain
- Magnum, P.I., a television series
- Thomas Magnum, the lead character
- Terry Wayne Allen, a professional wrestler also known as Magnum T.A.
- Magnum XL-200, a roller coaster at Cedar Point
- Magnum, a NATO brevity code for an AGM-88 or anti-radiation missile launch
- Yakovlev Yak-30 (1960) Magnum, an advanced trainer for the Soviet Air Forces that never went into production
- Magnum hops, used in the brewing of beer
- Magnum (Transformers), a fictional characters and commander of the Autobots
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