LTM may refer to:
- LTM, IATA code for Lethem Airport, Guyana
- LTM Recordings, British record label
- Long-term memory, memory that can be stored as little as a few days or as long as decades
- Last Twelve Months, a financial term also known as Trailing twelve months
- Local Traffic Manager, a web networking term synonymous with the term "Load Balancer."