Louis or Lou Johnson may refer to:
- Louis A. Johnson (1891–1966), second United States Secretary of Defense, from March 28, 1949 to September 19, 1950
- Louis Johnson (bassist) (born 1955), electric bassist for various artists as The Brothers Johnson, Quincy Jones and Michael Jackson
- Louis Johnson (poet), New Zealand poet
- Lou Johnson (born 1934), Major League Baseball player
- Lou Johnson (pitcher) (1869–1941), 19th century baseball player
- Lou Johnson (singer) (born 1941), American soul singer
- For Louis Stanley Johnson (1869–1937), see Stanley Johnson (London politician)
Famous quotes containing the words louis and/or johnson:
“Some people swallow the universe like a pill; they travel on through the world, like smiling images pushed from behind.”
—Robert Louis Stevenson (1850–1894)
“I am always sorry when any language is lost, because languages are the pedigree of nations.”
—Samuel Johnson (1709–1784)