Clinical Significance
The role of LTP in disease is less clear than its role in basic mechanisms of synaptic plasticity. However, alterations in LTP may contribute to a number of neurological diseases, including depression, Parkinson's disease, epilepsy, and neuropathic pain. Impaired LTP may also have a role in Alzheimer's disease and drug addiction.
Read more about this topic: Long-term Potentiation
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“The hysterical find too much significance in things. The depressed find too little.”
—Mason Cooley (b. 1927)