Lockout may refer to:
- Lockout (industry), a type of work stoppage
- Lockout (film), a 2012 science fiction action film
- Lockout chip, a computer chip in a video game system to prevent use of unauthorized software
- Lock-out device, part of a signaling system used on game shows
- Regional lockout, a barrier to prevent media use outside of a specific region
- Lockout-tagout, a procedure to prevent unsafe activation of machinery
- A period in some hostels during which guests are disallowed from the premises