Naturally Derived Local Anesthetics
- Saxitoxin
- Neosaxitoxin
- Tetrodotoxin
- Menthol
- Eugenol
Naturally occurring local anesthetics not derived from cocaine are usually neurotoxins, and have the suffix -toxin in their names. Unlike cocaine produced local anesthetics which are intracellular in effect, saxitoxin, neosaxitoxin & tetrodotoxin bind to the extracellular side of sodium channels.
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