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- Sun Ra, jazz musician (Birmingham)
- Max Rafferty, California Superintendent of Public Instruction from 1963 to 1971; education dean at Troy University (Troy)
- Howell Raines, former New York Times editor (Birmingham)
- Albert Rains, representative of Alabama's 7th congressional district (1945-1965) (Gadsden)
- Geoff Ramsey, voice actor and producer for Rooster Teeth Productions (Mobile)
- Theo Ratliff, center for the Charlotte Bobcats (Demopolis)
- Wayne Ray, author/poet (Talladega; Lineville)
- Ray Reach, jazz pianist, vocalist, arranger, composer, music producer, Director of Student Jazz Programs for the Alabama Jazz Hall of Fame (Birmingham)
- Gary Redus, baseball player (Decatur)
- Scottie Reynolds, Famous collegiate basketball player at Villanova
- Condoleezza Rice, former United States Secretary of State (Birmingham)
- Tony Richardson, NFL player- New York Jets (Daleville)
- Michael Rooker, actor (Jasper)
- Rich Boy, rapper (Mobile)
- Lionel Richie, singer (Tuskegee)
- Bob Riley, Governor of Alabama from 2003 to 2011 (Ashland)
- Alex RĂos, MLB outfielder- Chicago White Sox (Coffee County)
- Philip Rivers, college football star at North Carolina State University, NFL star with the San Diego Chargers (Decatur)
- David Robertson, pitcher for the New York Yankees (Birmingham)
- Martha Roby, representative from Alabama's 2nd congressional district since 2011 (Montgomery)
- Wayne Rogers, actor (Birmingham)
- Roy Rogers, former NBA player and current assistant coach for the Detroit Piston (Linden)
- Frank Rose, educator, former President of the University of Alabama (Tuscaloosa)
- Marie Rudisill, aka "The Fruitcake Lady", Truman Capote's aunt (Monroeville)
- Jeff Rutledge, former NFL quarterback (Birmingham)
- Debby Ryan, Actress (Huntsville)
- DeMeco Ryans, NFL player- Philadelphia Eagles (Bessemer)
Read more about this topic: List Of People From Alabama