List Of Mainstream Top 40 Number-one Hits Of 2003 (U.S.)
This is a list of the U.S. Billboard magazine Top 40 Mainstream number-ones of 2003.
| Issue Date | Song | Artist |
| January 4 | "Lose Yourself" | Eminem |
| January 11 | "Beautiful" | Christina Aguilera |
| January 18 | "Beautiful" | Christina Aguilera |
| January 25 | "Beautiful" | Christina Aguilera |
| February 1 | "Beautiful" | Christina Aguilera |
| February 8 | "I'm with You" | Avril Lavigne |
| February 15 | "I'm With You" | Avril Lavigne |
| February 22 | "I'm With You" | Avril Lavigne |
| March 1 | "I'm With You" | Avril Lavigne |
| March 8 | "All I Have" | Jennifer Lopez featuring LL Cool J |
| March 15 | "All I Have" | Jennifer Lopez featuring LL Cool J |
| March 22 | "All I Have" | Jennifer Lopez featuring LL Cool J |
| March 29 | "All I Have" | Jennifer Lopez featuring LL Cool J |
| April 5 | "In da Club" | 50 Cent |
| April 12 | "In da Club" | 50 Cent |
| April 19 | "In da Club" | 50 Cent |
| April 26 | "In da Club" | 50 Cent |
| May 3 | "When I'm Gone" | 3 Doors Down |
| May 10 | "Ignition" | R. Kelly |
| May 17 | "Rock Your Body" | Justin Timberlake |
| May 24 | "Rock Your Body" | Justin Timberlake |
| May 31 | "Rock Your Body" | Justin Timberlake |
| June 7 | "Rock Your Body" | Justin Timberlake |
| June 14 | "Bring Me to Life" | Evanescence featuring Paul McCoy |
| June 21 | "Bring Me to Life" | Evanescence featuring Paul McCoy |
| June 28 | "Miss Independent" | Kelly Clarkson |
| July 5 | "Miss Independent" | Kelly Clarkson |
| July 12 | "Miss Independent" | Kelly Clarkson |
| July 19 | "Miss Independent" | Kelly Clarkson |
| July 26 | "Miss Independent" | Kelly Clarkson |
| August 2 | "Miss Independent" | Kelly Clarkson |
| August 9 | "Where Is the Love?" | The Black Eyed Peas featuring Justin Timberlake |
| August 16 | "Crazy in Love" | Beyoncé featuring Jay-Z |
| August 23 | "Where Is the Love?" | The Black Eyed Peas featuring Justin Timberlake |
| August 30 | "Where Is the Love?" | The Black Eyed Peas featuring Justin Timberlake |
| September 6 | "Where Is the Love?" | The Black Eyed Peas featuring Justin Timberlake |
| September 13 | "Where Is the Love?" | The Black Eyed Peas featuring Justin Timberlake |
| September 20 | "Where Is the Love?" | The Black Eyed Peas featuring Justin Timberlake |
| September 27 | "Where Is the Love?" | The Black Eyed Peas featuring Justin Timberlake |
| October 4 | "Shake Ya Tailfeather" | Nelly, P. Diddy and Murphy Lee |
| October 11 | "Shake Ya Tailfeather" | Nelly, P. Diddy and Murphy Lee |
| October 18 | "Shake Ya Tailfeather" | Nelly, P. Diddy and Murphy Lee |
| October 25 | "Here Without You" | 3 Doors Down |
| November 1 | "Here Without You" | 3 Doors Down |
| November 8 | "Baby Boy" | Beyoncé featuring Sean Paul |
| November 15 | "Here Without You" | 3 Doors Down |
| November 22 | "Here Without You" | 3 Doors Down |
| November 29 | "Here Without You" | 3 Doors Down |
| December 6 | "Here Without You" | 3 Doors Down |
| December 13 | "Hey Ya!" | OutKast |
| December 20 | "Hey Ya!" | OutKast |
| December 27 | "Hey Ya!" | OutKast |
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