List of Epidemics

This article is a list of epidemics of infectious disease. Widespread and chronic complaints such as heart disease and allergy are not included if they are not thought to be infectious.

Death toll Region Years Name Species Citation
Egypt -8350-01-011650 BC–-8450-01-011550 BC bubonic plague or influenza
Greece -9570-01-01430 BC–-9573-01-01427 BC Plague of Athens typhoid or typhus
5,000,000 Roman Empire 00165-01-01165–00180-01-01180 Antonine Plague smallpox
Roman Empire 00251-01-01251–00270-01-01270 Plague of Cyprian smallpox
25,000,000 Eastern Roman (Byzantine) Empire 00541-01-01541–00542-01-01542 Plague of Justinian bubonic plague
25,000 Palestine 00639-01-01639 Plague of Emmaus bubonic plague
100,000,000 Europe, Asia 1338–1351 Black Death bubonic plague
Russia 1353 plague
France 1466 Paris plague
England 1485, 1507, 1516, 1529, 1551 English sweating sickness unknown
Spain 1489 Granada typhus
Hispaniola 1493 influenza
Iceland 1494–1495 plague
England 1498 plague
Italy 1505–1530 typhus
90-95% of native population The Americas 1500–1900 smallpox, measles, typhoid, etc.
Hispaniola 1507 smallpox
England 1509–1510 plague
Puerto Rico 1515 smallpox
Hispaniola 1518 smallpox
Mexico 1520 smallpox
Germany 1527 plague
Peru 1527–1530 smallpox
Mexico, Peru 1530–1531 measles
Mexico, Peru 1546 typhus
Brazil 1555 smallpox
Spain 1557 Valencia plague
Mexico, Peru 1558–1559 influenza
Ottoman Empire 1560 Istanbul plague
Chile 1561 smallpox
England 1563–1564 plague
Russia 1570 Moscow plague
Scotland 1574 Edinburgh plague
Mexico 1576 viral hemorrhagic fever
Seneca nation 1592–1596 measles
Spain 1596–1602 plague
South America 1600–1650 malaria
England 1603 London plague
Egypt 1609 plague
Thirteen Colonies 1617–1619 Massachusetts Bay area smallpox
Italy 1629–1631 Italian plague of 1629–1631 plague
Wyandot people 1630 in Ontario smallpox
Thirteen Colonies 1633 Plymouth Colony smallpox
Thirteen Colonies 1634 Connecticut River area smallpox
England 1636 Newcastle plague
China 1641–1644 helped end the Ming Dynasty plague
Spain 1647–1652 Great Plague of Seville plague
South America 1648 yellow fever
Italy 1656 Naples plague
Thirteen Colonies 1657 Boston, Massachusetts measles
Netherlands 1663–1664 Amsterdam plague
100,000 England 1665–1666 Great Plague of London plague
40,000 France 1668 plague
Spain 1676–1685 plague
Austria 1679 Great Plague of Vienna plague
Thirteen Colonies 1687 Boston, Massachusetts measles
Thirteen Colonies 1690 New York City yellow fever
Canada, New France 1702–1703 smallpox
Sweden 1710–1711 Stockholm plague
Thirteen Colonies 1713 Boston, Massachusetts measles
Thirteen Colonies 1713–1715 New England and the Great Lakes measles
Canada, New France 1714–1715 measles
France 1720–1722 Great Plague of Marseille plague
Thirteen Colonies 1721–1722 Boston, Massachusetts smallpox
Thirteen Colonies 1729 Boston, Massachusetts measles
Spain 1730 Cadiz yellow fever
Thirteen Colonies 1732–1733 influenza
Canada, New France 1733 smallpox
Balkans 1738 Great Plague of 1738 plague
Thirteen Colonies 1738 South Carolina smallpox
Thirteen Colonies 1739–1740 Boston, Massachusetts measles
Italy 1743 Messina plague
Thirteen Colonies 1747 CT, NY, PA, SC measles
North America 1755–1756 smallpox
North America 1759 measles
North America, West Indies 1761 influenza
Russia 1770–1772 Russian plague of 1770–1772 plague
Pacific Northwest natives 1770s smallpox
North America 1772 measles
North America 1775 particularly in the northeast unknown cause
England 1775–1776 influenza
Spain 1778 Cadiz dengue fever
Plains Indians 1780–1782 North American smallpox epidemic smallpox
Pueblo Indians 1788 smallpox
United States 1788 Philadelphia and New York measles
New South Wales, Australia 1789–1790 amongst the Aborigines smallpox
United States 1793 Vermont influenza and epidemic typhus
United States 1793 Virginia influenza
United States 1793–1798 Yellow Fever Epidemic of 1793, resurgences yellow fever
Spain 1800–1803 yellow fever
Ottoman Empire, Egypt 1801 bubonic plague
United States 1803 New York yellow fever
Egypt 1812 plague
Ottoman Empire 1812 Istanbul plague
Malta 1813 plague
Romania 1813 Bucharest plague
Ireland 1816–1819 typhus
>>100,000 Asia, Europe 1816–1826 first cholera pandemic cholera
United States 1820–1823 arising near Schuylkill River fever
Spain 1821 Barcelona yellow fever
New South Wales, Australia 1828 amongst the Aborigines smallpox
Netherlands 1829 Groningen epidemic malaria
South Australia 1829 smallpox
Iran 1829–1835 bubonic plague
>>100,000 Asia, Europe, North America 1829–1851 second cholera pandemic cholera
Egypt 1831 cholera
Plains Indians 1831–1834 smallpox
England, France 1832 London, Paris cholera
North America 1832 New York City, Montreal other cities cholera
United States 1833 Columbus, Ohio cholera
United States 1834 New York City cholera
Egypt 1834–1836 bubonic plague
United States 1837 Philadelphia typhus
Great Plains 1837–1838 1837-38 smallpox epidemic smallpox
Dalmatia 1840 plague
South Africa 1840 Cape Town smallpox
United States 1841 especially severe in the South yellow fever
20,000+ Canada 1847–1848 Typhus epidemic of 1847 epidemic typhus
United States 1847 New Orleans yellow fever
worldwide 1847–1848 influenza
Egypt 1848 cholera
North America 1848–1849 cholera
United States 1850 yellow fever
North America 1850–1851 influenza
United States 1851 Illinois, the Great Plains, and Missouri cholera
United States 1852 New Orleans yellow fever
1,000,000 Russia 1852–1860 third cholera pandemic cholera
Ottoman Empire 1853 what is now Yemen plague
616 England 1854 Broad Street cholera outbreak cholera
United States 1855 yellow fever
worldwide 1855–1950 Third Pandemic bubonic plague
Portugal 1857 Lisbon yellow fever
Victoria, Australia 1857 smallpox
Europe, North America, South America 1857–1859 influenza
Middle East 1863–1879 fourth cholera pandemic cholera
Egypt 1865 cholera
Russia, Germany 1866–1867 cholera
Australia 1867 Sydney measles
Iraq 1867 plague
Argentina 1852–1871 Buenos Aires yellow fever
Germany 1870–1871 smallpox
40,000 Fiji 1875 Fiji measles
Russian Empire 1877 Baku, now part of Azerbaijan plague
Egypt 1881 cholera
>>9,000 India, Germany 1881–1896 fifth cholera pandemic cholera
3,164 Montreal 1885 smallpox timeline
1,000,000 worldwide 1889–1890 Russian flu influenza
Congo Basin 1896–1906 trypanosomiasis
>>800,000 Europe, Asia, Africa 1899–1923 sixth cholera pandemic cholera
113 San Francisco 1900–1904 Third plague pandemic bubonic plague
West Africa 1900 yellow fever
Uganda 1900–1920 trypanosomiasis
Egypt 1902 cholera
India 1903 plague
China 1910–1912 Manchuria bubonic plague
75,000,000 worldwide 1918–1920 1918 flu pandemic influenza
Russia 1918–1922 typhus
Egypt 1942–1944 malaria
China 1946 Manchuria bubonic plague
Egypt 1946 relapsing fever
Egypt 1947 cholera
2,000,000 worldwide 1957–1958 Asian flu influenza
worldwide 1961–present seventh cholera pandemic cholera
1,000,000 worldwide 1968–1969 Hong Kong flu influenza
Yugoslavia 1972 1972 outbreak of smallpox in Yugoslavia smallpox
United States 1972–1973 London flu influenza
15,000 India 1974 1974 smallpox epidemic of India smallpox
25,000,000 worldwide 1981–present HIV/AIDS pandemic HIV/AIDS
South America 1990s cholera
52 India 1994 1994 plague epidemic in Surat plague
West Africa 1996 meningitis
Central America 2000 dengue fever
Nigeria 2001 cholera
South Africa 2001 cholera
775 Asia 2002–2003 SARS SARS coronavirus
Algeria 2003 plague
Afghanistan 2004 leishmaniasis
Bangladesh 2004 cholera
Indonesia 2004 dengue fever
Senegal 2004 cholera
Sudan 2004 ebola
Mali 2005 yellow fever
19 Singapore 2005 2005 dengue outbreak in Singapore dengue fever
Angola 2006 Luanda cholera
Congo 2006 Ituri Province plague
India 2006 malaria
50+ India 2006 2006 dengue outbreak in India dengue fever
India 2006 Chikungunya outbreaks Chikungunya virus
50+ Pakistan 2006 2006 dengue outbreak in Pakistan dengue fever
Philippines 2006 dengue fever
Congo 2007 Mweka ebola
Ethiopia 2007 cholera
49 India 2007 cholera
10 Iraq 2007 2007 Iraq cholera outbreak cholera
Nigeria 2007 polio
Puerto Rico, Dominican Republic, Mexico 2007 dengue fever
Somalia 2007 cholera
Uganda 2007 ebola
Vietnam 2007 cholera
Brazil 2008 dengue fever
Cambodia 2008 dengue fever
Chad 2008 cholera
China 2008 hand, foot and mouth disease
Madagascar 2008 bubonic plague
Philippines 2008 dengue fever
Vietnam 2008 cholera
4,293 Zimbabwe 2008–2009 2008–2009 Zimbabwean cholera outbreak cholera
18 Bolivia 2009 2009 Bolivian dengue fever epidemic dengue fever
India 2009 2009 Gujarat hepatitis outbreak hepatitis B
Queensland, Australia 2009 dengue fever
worldwide 2009 Mumps outbreaks in the 2000s mumps
931 West Africa 2009–2010 2009-2010 West African meningitis outbreak meningitis
14,286 worldwide 2009–2010 2009 flu pandemic influenza
6,500+ (January 2012) Hispaniola 2010–present 2010–2011 Haiti cholera outbreak cholera
Congo 2011–present measles
81 Vietnam 2011–present hand, foot and mouth disease
350+ Pakistan 2011–present 2011 dengue outbreak in Pakistan dengue fever


Death toll Region Years Name Species Citation

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