Ligase - Classification

Classification

Ligases are classified as EC 6 in the EC number classification of enzymes. Ligases can be further classified into six subclasses:

  • EC 6.1 includes ligases used to form carbon-oxygen bonds
  • EC 6.2 includes ligases used to form carbon-sulfur bonds
  • EC 6.3 includes ligases used to form carbon-nitrogen bonds (including argininosuccinate synthetase)
  • EC 6.4 includes ligases used to form carbon-carbon bonds
  • EC 6.5 includes ligases used to form phosphoric ester bonds
  • EC 6.6 includes ligases used to form nitrogen-metal bonds

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