Laminin - Types

Types

Fifteen laminin trimers have been identified. The laminins are combinations of different alpha-, beta-, and gamma-chains.

  • There are five forms of alpha-chains: LAMA1, LAMA2, LAMA3, LAMA4, LAMA5
  • There are four of beta-chains: LAMB1, LAMB2, LAMB3, LAMB4
  • There are three of gamma-chains: LAMC1, LAMC2, LAMC3

Laminins were previously numbered - e.g. Laminin-1, Laminin-2, Laminin-3 - but the nomenclature was recently changed to describe which chains are present in each isoform. For example, laminin-511 contains an α5-chain, a β1-chain and a γ1 chain.

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