Knoblauch, Knobloch, Knoblock, or Knoblaugh, is a German surname meaning garlic. It may refer to:
- Eduard Knoblauch, German architect
- Edward Knoblock, American dramatist
- Karl-Hermann Knoblauch, German physicist
- Mary Bookstaver Knoblauch, American feminist
- Chuck Knoblauch, American baseball player
- Charlotte Knobloch, Vice President of the European Jewish Congress
- Glen Gray Knoblauch, American jazz saxophonist
- Jim Knobeloch, American actor
- Thoralf Knobloch, German artist
- Valentin Knobloch, German judoka
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