Kirwan may refer to:
- One of the fourteen Tribes of Galway
- Kirwan, Queensland, suburb in the city of Townsville, Queensland, Australia
- Château Kirwan, Bordeaux wine producer, formerly named simply Kirwan
- Kairouan, also known as Kirwan, the capital of the Kairouan Governorate in Tunisia
- People
- A. D. Kirwan (1904–1971), former professor, administrator, coach and president of the University of Kentucky
- Danny Kirwan, guitarist with Fleetwood Mac from 1968 to 1972
- Dervla Kirwan, actress
- Eilis Kirwan, Irish filmmaker
- James Kirwan was a physician to Louis XV
- John Kirwan (disambiguation), several persons of this name
- Larry Kirwan, musician and playwright best known for his work with Black 47
- Richard Kirwan of Galway, prominent philosopher and chemist
- Richard Bui Kirwan of Cregg Castle, a soldier with Dillon's Regiment at Fontenoy
- William E Kirwan, Chancellor of the University of Maryland System
- William F Kirwan, American economist known for his work in sports economics
- Nicholas Murray (1802–1861), Irish-American writer, whose pseudonym was Kirwan