Khachatryan or Khachatrian (Armenian: Խաչատրյան) is an Armenian surname. It can refer to the following people:
- Ara Khachatryan, an Armenian weightlifter
- Garegin Khachatryan, an Armenian sculptor, artist and a dissident
- Rafik Khachatryan, an Armenian sculptor
- Romik Khachatryan, an Armenian football player
- Sergey Khachatryan, an Armenian violinist
- Suren Khachatryan, an Armenian politician
- Vardan Khachatryan, an Armenian football player
- Taron Khachatryan, an Armenian sprinter
and objects:
- 18174 Khachatryan
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