Keratinocyte - Role in Wound Healing

Role in Wound Healing

Wounds to the skin will be repaired in part by the migration of keratinocytes to fill in the gap created by the wound. The first set of keratinocytes to participate in that repair come from the bulge region of the hair follicle and will only survive transiently. Within the healed epidermis they will be replaced by keratinocytes originating from the epidermis.

At the opposite, epidermal keratinocytes, can contribute to de novo hair follicle formation during the healing of large wounds.

Keratinocytes migrate with a rolling motion during the process of wound healing.

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