KBSI is the Fox-affiliated television station for the Missouri Bootheel, Southern Illinois, and Western Kentucky's Jackson Purchase. Licensed to Cape Girardeau, Missouri, it broadcasts a high definition digital signal on UHF channel 22 (or virtual channel 23.1 via PSIP) from a transmitter in unincorporated Cape Girardeau County north of the city. The station can also be seen on Comcast channel 8, Charter channel 9, and Mediacom channel 10.
There is a high definition feed provided on Comcast digital channel 434, Mediacom digital channel 710, and Charter digital channel 782. Owned by the Sinclair Broadcast Group, the station operates MyNetworkTV affiliate WDKA (its license is locally owned) through a local marketing agreement (LMA). The two outlets share studios on Enterprise Street in Cape Girardeau. Syndicated programming on KBSI includes Two and a Half Men, Judge Judy, The People's Court, and Swift Justice with Nancy Grace among others.