Jules is the French form of the Latin "Julius" (e.g. Jules César, the French name for Julius Caesar). It may refer to:
- Didacus Jules, a St. Lucian educator
- Gary Jules (b. 1969), an American singer-songwriter
- Jules Breton (1827–1906), French Realist painter
- Jules Brunet, a French General
- Jules Feiffer, an American cartoonist
- Jules Gervais-Courtellemont, French war photographer from World War I
- Jules Maenen, a Dutch road bicycle and track cyclist
- Jules Rimet, former FIFA president, after whom the Jules Rimet Trophy was named
- Jules Védrines (1881-1919), French aviator
- Jules Verne, a French author
- Jules Winnfield, a fictional character in the film Pulp Fiction
- JULES, Joint UK Land Environment Simulator
- Jules, a robot by Hanson Robotics
- Jules Cobb, the main character of the US television series Cougar Town