IRMA may refer to:
- Institute of Rural Management, Anand, a management school for rural development in the state of Gujarat, India
- International Recording Media Association
- International Rectal Microbicide Advocates
- Internationalization Resource Management Application, a web-based application for the translation of open source software maintained by Linspire
- Intraretinal microvascular abnormalities, a component of diabetic eye disease
- Irish Recorded Music Association
- IRMA board, a brand name of mainframe terminal emulators
- Immunoradiometric assay, a type of biochemical test
- Intreprinderea de Reparatii Material Aeronautic, a Romanian aircraft manufacturer.