Site of Secretion
The intrinsic factor is secreted by the stomach. It is present in the gastric juice as well as in the gastric mucous membrane. The optimum pH for its action is 7 and it is inactivated at temperatures above 45 °C. It does not necessarily run parallel with the amount of HCl or pepsin in the gastric juice. So in some cases, the intrinsic factor may be present even if there is no HCl or Pepsin or vice versa. The site of formation of the intrinsic factor varies in different species. In pigs it is obtained from the pylorus and beginning of the duodenum. In human beings it is present in the fundus and body of the stomach.
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“It is not menstrual blood per se which disturbs the imagination—unstanchable as that red flood may be—but rather the albumen in the blood, the uterine shreds, placental jellyfish of the female sea. This is the chthonian matrix from which we rose. We have an evolutionary revulsion from slime, our site of biologic origins. Every month, it is woman’s fate to face the abyss of time and being, the abyss which is herself.”
—Camille Paglia (b. 1947)
“It is not menstrual blood per se which disturbs the imagination—unstanchable as that red flood may be—but rather the albumen in the blood, the uterine shreds, placental jellyfish of the female sea. This is the chthonian matrix from which we rose. We have an evolutionary revulsion from slime, our site of biologic origins. Every month, it is woman’s fate to face the abyss of time and being, the abyss which is herself.”
—Camille Paglia (b. 1947)