International Nonproprietary Name - Name Stems

Name Stems

Drugs from the same therapeutic or chemical class are usually given names with the same stem. Stems are mostly placed word-finally, but in some cases word-initial stems are used. They are collected in a publication informally known as the Stem Book.

Examples are:

  • -coxib for COX-2 inhibitors, a type of anti-inflammatory drugs (e.g. celecoxib)
  • -mab for monoclonal antibodies (e.g. infliximab); see Nomenclature of monoclonal antibodies
  • -olol for beta blockers (e.g. atenolol)
  • -oxetine for fluoxetine derivatives, a group of antidepressants
  • -pril for ACE inhibitors (e.g. captopril)
  • -vastatin for HMG-CoA reductase inhibitors, a group of cholesterol lowering agents (e.g. simvastatin)
  • io- for iodine containing radiopharmaceuticals (e.g. iobenguane)

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Famous quotes containing the word stems:

    Approximately 80% of our air pollution stems from hydrocarbons released by vegetation, so let’s not go overboard in setting and enforcing tough emission standards from man-made sources.
    Ronald Reagan (b. 1911)

    One who pressed forward incessantly and never rested from his labors, who grew fast and made infinite demands on life, would always find himself in a new country or wilderness, and surrounded by the raw material of life. He would be climbing over the prostrate stems of primitive forest-trees.
    Henry David Thoreau (1817–1862)