An internal ribosome entry site, abbreviated IRES, is a nucleotide sequence that allows for translation initiation in the middle of a messenger RNA (mRNA) sequence as part of the greater process of protein synthesis. Usually, in eukaryotes, translation can be initiated only at the 5' end of the mRNA molecule, since 5' cap recognition is required for the assembly of the initiation complex.
Read more about Internal Ribosome Entry Site: History, Location, Activation, Mechanism, Testing, Types
Famous quotes containing the words internal, entry and/or site:
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—Harriet Beecher Stowe (1811–1896)
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—Henry David Thoreau (1817–1862)