INADL

INADL

Identifiers Symbols INADL; Cipp; InaD-like; PATJ; hINADL External IDs OMIM: 603199 MGI: 1277960 HomoloGene: 72199 GeneCards: INADL Gene

Gene Ontology
Molecular function	• protein binding
Cellular component	• plasma membrane • tight junction • apical plasma membrane • perinuclear region of cytoplasm
Biological process	• cell junction assembly • intracellular signal transduction • cell-cell junction organization • tight junction assembly
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 10207 12695 Ensembl ENSG00000132849 ENSMUSG00000061859 UniProt Q8NI35 A2ADL9 RefSeq (mRNA) NM_005799 NM_001005784 RefSeq (protein) NP_795352 NP_001005784 Location (UCSC) Chr 1:
62.21 – 62.63 Mb Chr 4:
98.4 – 98.72 Mb PubMed search

InaD-like protein is a protein that in humans is encoded by the INADL gene.

This gene encodes a protein with multiple PDZ domains. PDZ domains mediate protein-protein interactions, and proteins with multiple PDZ domains often organize multimeric complexes at the plasma membrane. This protein localizes to tight junctions and to the apical membrane of epithelial cells. A similar protein in Drosophila is a scaffolding protein which tethers several members of a multimeric signaling complex in photoreceptors.