Illinois Route 143 is an east–west state highway in southwestern Illinois. Its western terminus is at U.S. Route 67 (very near, but not at the termini of Illinois Route 100 and Illinois Route 140) in Alton. Its eastern terminus at Illinois Route 127 at a rural intersection west of Tamalco. This is a distance of 47.96 miles (77.18 km).
Read more about Illinois Route 143: Route Description, History
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