Human Equivalent - Animal Models in Chemistry and Medicine

Animal Models in Chemistry and Medicine

Animal models are used to learn more about a disease, its diagnosis and its treatment, with animal models predicting human toxicity in up to 71% of cases. The human equivalent dose (HED) or human equivalent concentration (HEC) is the quantity of a chemical that, when administered to humans, produces an effect equal to that produced in test animals by a smaller dose. Calculating the HED is a step in carrying out a clinical trial of a pharmaceutical drug.

Read more about this topic:  Human Equivalent

Famous quotes containing the words animal, models, chemistry and/or medicine:

    Mind and spirit together make up that which separates us from the rest of the animal world, that which enables a man to know the truth and that which enables him to die for the truth.
    Edith Hamilton (1867–1963)

    The parents who wish to lead a quiet life I would say: Tell your children that they are very naughty—much naughtier than most children; point to the young people of some acquaintances as models of perfection, and impress your own children with a deep sense of their own inferiority. You carry so many more guns than they do that they cannot fight you. This is called moral influence and it will enable you to bounce them as much as you please.
    Samuel Butler (1835–1902)

    Science with its retorts would have put me to sleep; it was the opportunity to be ignorant that I improved. It suggested to me that there was something to be seen if one had eyes. It made a believer of me more than before. I believed that the woods were not tenantless, but choke-full of honest spirits as good as myself any day,—not an empty chamber, in which chemistry was left to work alone, but an inhabited house,—and for a few moments I enjoyed fellowship with them.
    Henry David Thoreau (1817–1862)

    I hold it that a little rebellion, now and then, is a good thing, and as necessary in the political world as storms in the physical.... It is a medicine necessary for the sound health of government.
    Thomas Jefferson (1743–1826)