Hotspur is a nickname of Sir Henry Percy (1364–1403), known as Harry Hotspur, eldest son of the 1st Earl of Northumberland
Hotspur may also refer to:
- A character in Shakespeare's Henry IV, Part 1
- Football clubs:
- Holyhead Hotspur F.C.
- Pietà Hotspurs F.C.
- Tottenham Hotspur F.C.
- General Aircraft Hotspur, a WW2 glider
- Hotspur, British Railways class 7 "Britannia" locomotive 70011
- HMS Hotspur, several British ships
- Land Rover Tangi, a British Army armoured Land Rover used in Northern Ireland
- The Hotspur (comics), former British boys' weekly comic and annual published by D. C. Thomson & Co.
- Hotspur, a three-issue Eclipse comic book series
- Hotspur Technologies, Inc., a medical device company in Mountain View, California
- Hotspur Primary School, Newcastle upon Tyne